Effect of Erythropoiesis-Stimulating Agents on Blood Pressure in Pre-Dialysis Patients

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Effect of Erythropoiesis-Stimulating Agents on Blood Pressure in Pre-Dialysis Patients

INTRODUCTION Erythropoiesis-Stimulating Agents (ESA) are hypothesized to increase cardiovascular mortality in patients with chronic kidney disease. One of the proposed mechanisms is the elevation of blood pressure (BP) by ESA. Therefore, we aimed to determine whether the use of ESA was associated with antihypertensive treatment and higher BP. MATERIALS AND METHODS In this cohort 502 incident ...

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Systematic review of the impact of erythropoiesis-stimulating agents on fatigue in dialysis patients.

BACKGROUND One of the cardinal symptoms of anemia in chronic kidney disease (CKD) patients is fatigue. Recently, results from Trial to Reduce Cardiovascular Events with Aranesp Therapy (TREAT) raised questions about the role of erythropoiesis-stimulating agents (ESAs) in improving fatigue and the appropriate hemoglobin (Hb) target in anemic patients with CKD. These discussions should be conside...

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Effect of long-acting erythropoiesis-stimulating agents on hemoglobin levels at the initiation of dialysis

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2013

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0084848